Glazebrook, Jane
The main focus of our research is on understanding the signal
transduction network controlling plant responses to pathogen attack.
We use expression profiles as detailed descriptions of mutant
phenotypes. By obtaining profiles from many mutants with defense
signaling defects, and comparing them using various pattern-recognition
methods, we build models of the signaling network. We also use reverse
genetics to test pathogen-responsive genes for roles in defense.
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